News

Aug 2022 – Meg, Isaac, and Lea published their paper “Internally controlled RNA sequencing comparisons using nucleoside recoding chemistry” in Nucleic Acids Research. Congratulations on a job well done!

 

Mar 2022 – Welcome to our newest graduate student, Alexandra Zhang!

 

Sept 2021 – Congratulations to Josh whose paper “STL-seq reveals pause-release and termination kinetics for promoter-proximal paused RNA polymerase II transcripts” was published in Molecular Cell!

 

April 2021 – Welcome to our newest lab member and graduate student, Andreas Pintado-Urbanc!

 

Mar 2020 – Welcome to our newest lab member, Isaac Vock!

 

Mar 2020 – Martin Machyna and Lea Kiefer publish their paper “Enhanced nucleotide chemistry and toehold nanotechnology reveals lncRNA spreading on chromatin” in Nat Struct Mol Biol.

 

Oct 2019 – Tyler Smith and Madeline Zoltek publish their paper “Reengineering a tRNA methaltransferase to covalently capture new RNA substrates” in JACS.

 

April 2019 – Lea Kiefer published a viewpoint on “Stella’s Role in Oocyte DNA Methylation Suggests Additional Activities of DNMT1” in Biochemistry.

 

April 2019 – Daniele Canzio in collaboration with Erin Duffy publishes his paper “Antisense lncRNA Transcription Mediates DNA Demethylation to Drive Stochastic Protocadherin α Promoter Choice” in Cell.

 

Nov 2018 – Peter Wang, Alec Sexton and William Culligan publish their paper “Carbodiimide reagents for the chemical probing of RNA structure in cells ” in RNA.

 

Oct 2018 – Erin Duffy and Jeremy Schofield publish a comprehensive review on exploiting the chemistry of 4-thiouridine to study RNA population dynamics.

 

Oct 2018 – Josh successfully passed his qualifying exam!

 

Oct 2018 – Congratulations to Lea Kiefer and Jeremy Schofield whose communication “Expanding the Nucleotide Recoding Toolkit: Revealing RNA Population Dynamics with 6-Thioguanosine.” was accepted into JACS.

 

May 2018 – We are congratulating our graduating undergraduates Peter and Maddie, and first graduate student of the lab, Erin!

 

May 2018 – Welcoming our new lab members Josh, Michelle and Tyler&Laura’s first son Jack Wesley!

 

April 2018 – Lea Kiefer receives the American Heart Association Predoctoral Fellowship!

 

Feb 2018 – Congratulations to Erin Duffy for a great and first of its kind “Simon Lab thesis defense”.

 

Jan 2018 – Congratulations to Jeremy Schofield, Erin Duffy, Lea Kiefer and Meg Sullivan whose manuscript “TimeLapse-seq: Adding a temporal dimension to RNA sequencing through nucleoside recoding“ was published in Nature Methods.

 

Nov 2017 – Check out Martin Machyna’s review on “Catching RNAs on chromatin using hybridization capture methods“ in Briefings in Functional Genomics.

 

Oct 2017 – Meg Sullivan passed her qualifying exam, congrats!

 

Aug 2017 – Congratulations to Alec Sexton, Peter Wang and Michael Rutenberg-Schoenberg whose manuscript on RNA chemical probing to infer structure was published in Biochemistry.

 

Aug 2017 – Congratulations to Erin Duffy whose collaboration with the Flavell lab at Yale University just got published in Nature.

 

Mar 2017 – Erin Duffy is awarded the Collegiate Woman of Innovation Award by the Connecticut Technology Council.

 

Feb 2016 – Congrats to Will Culligan for passing his qualifying exam!

 

Dec 2016 – Erin Duffy’s updated protocol using efficient chemistry to track RNA populations is now available in Current Protocols in Chemical Biology.

 

Nov 2016 – Lea Kiefer passed her qualifying exam, congrats!

 

Aug 2016 – Erin Duffy presented at the Regulatory and ncRNA Conference at CSH.

 

Jun 2016 – Martin Machyna receives the Charles H. Revson Senior Fellowship in biomedical science!

 

May 2016 – Congrats to Tyler Smith for becoming a McDougal Teaching Fellow!

 

Apr 2016 – We have a new lab member: Congratulation to Martin Machyna for the birth of his first child, Oliver!

 

Mar 2016 – Erin Duffy was awarded a Scholar Award from the Philanthropic Education Organization.

 

Nov 2015 – Jeremy Schofield passed his qualifying exam, congrats!

 

Sep 2015 – Congrats to Erin Duffy and Michael Rutenberg-Schoenberg whose paper on using efficient and reversible chemistry to track distinct RNA populations was published in Molecular Cell.

 

Nov 2014 – Congratulations to Tyler Smith for passing his qualifying exam!

 

Sept 2013 – Tyler Smith just became a Gruber Science Fellow, congrats!

 

Oct 2013 – Congrats to Erin Duffy for passing her qualifying exam!

 

Mar 2012 –Erin Duffy receives the NSF Graduate Research Fellowship.